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Senior Scientist

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Salary: £40,451 per annum plus benefits

Location:  South Mimms

Contract: Permanent/Full-time

Ref: 222152

The MHRA is transforming. Through enabling innovation, making the right judgements of the benefits and risks of medical products and forging the right partnerships in the UK and internationally, it aims to deliver world class regulation and improved outcomes for UK patients.

We currently have an exciting full-time opportunity for a Senior Scientist to join our Standards Lifecycle sub-group in the Scientific Research and Innovation group on a fixed-term basis (13.5 months contract).

The role is funded for 13.5 months by a collaboration with the United States Pharmacopoeial Commission, to support the development of physical reference materials to serve as system suitability standards for therapeutic monoclonal antibodies (mAbs). The role aims to progress three projects: (1) development of a bespoke mAb reference material containing high molecular weight variants, to support testing for such variants in therapeutic mAbs; (2) development of a proteolyzed mAb preparation to support peptide mapping of therapeutic mAbs; and (3) development of a degraded mAb preparation to support testing for charged variants in therapeutic mAbs.

Who are we looking for?

The successful candidate will be expected to have skills and expertise in protein chemistry and modification, and physicochemical characterisation methods such HPLC, mass spectrometry and capillary electrophoresis. In addition, you will understand the role of pharmacopoeia, including the role of physical reference materials, and the principles of system suitability. 

You will have experience of leading complex collaborative scientific projects management, and of working under a quality management system. You will be able to engage with internal and external stakeholders and be adept at gathering, analysing, and presenting information to a range of audiences. You will be a confident self-starter, who can operate both autonomously and collaboratively. 

Please use this link to apply: Senior Scientist – £40,451 p.a. + benefits – Civil Service Jobs – GOV.UK

Closing date: 28 July 2022.

Click Here to Apply For The Job



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