Closing Date: 23 November 2023
Job description
We are seeking an individual to join the Patient Derived Models (PDM) team in the Breast Cancer Now (BCN) Research Unit based at the Innovation Hub, Guy’s Caner Centre, KCL Guy’s Campus.
We wish to hire EITHER:
- A Research Technician (Grade 4: £32,179 – £35,596 per annum, inclusive of London weighting allowance)
OR
- A Senior Research Technician (Grade 5: £36,532 – £41,299 per annum, inclusive of London weighting allowance)
Skills, knowledge, and experience
Research Technician Role (Grade 4)
Essential criteria
- BSc (Hons) degree or equivalent in a relevant subject.
- UK Home Office Module A + B training completed.
- Prior education/exposure to the cancer research field. Previous experience working in the cancer research field is highly desirable.
- Proven experience working within a research laboratory environment, working on biomedical research projects.
- Experience working with animals (particularly mice) within a biomedical research environment
- Prior experience in various dosing techniques for delivery of in vivo therapeutics (this may include: intraperitoneal injection, oral gavage, IV injection).
- Knowledge of 2D and 3D cell culture and cell biology techniques. Prior experience is desirable.
- Proven ability to work independently, to work under pressure to meet deadlines and to manage and prioritize own workload.
- Experience in the design, conduct, optimisation and analysis of biomedical experiments.
- Proven experience of preparing scientific graphs and figures, writing scientific reports and presenting scientific research.
- Computer literacy. Experience working with MS Excel is essential. Prior experience working with mouse database management systems and scientific graphing software such as GraphPad Prism is highly desirable.
- Experience working with large data sets.
Research Technician Role (Grade 5)
Essential criteria
- BSc (Hons) degree or equivalent in a relevant subject.
- Holds a UK Personal Licence for Home Office Modules A, B and C
- Extensive experience of working with mice and studies involving in vivo models in the breast cancer setting.
- Previous extensive experience working with tumour xenograft and PDX models. In particular, experience of trocar implantation and monitoring tumour growth in the mammary fat pad.
- Expertise in various dosing techniques for delivery of cancer therapeutics (including: intraperitoneal injection, oral gavage, IV injection).
- Surgical experience: including ability to demonstrate aseptic surgical techniques and experience of induction and maintenance of anesthesia.
- Experience performing in vivo whole animal imaging (IVIS) and analysis of IVIS data.
- Experience performing RNA and DNA extractions, STR profiling and 2D or 3D cell culture.
- Experience working in a multidisciplinary team and co-ordinating work across multiple clinical, laboratory and animal facility sites.
- Proven ability to work independently, to work under pressure to meet deadlines and to manage and prioritize own workload. Experience in the design, conduct, optimisation and analysis of in vivo experiments is essential.
- Proven experience of preparing scientific figures and presenting scientific work. Experience working with large data sets and excellent computer literacy (including proficiency in graph pad prism) is essential.
- Previous experience in a technical role with involvement in laboratory management. Including: preparation of drugs for in vivo experiments and stock solutions, ordering reagents, maintenance of equipment and management of laboratory inventories and databases.