The Regulatory Genomics laboratory uses genomics, bioinformatics, molecular and biochemical techniques to identify how chromatin modifiers function with RNA to regulate cell differentiation. The lab currently comprises the principal investigator, three postdoctoral research associates, and three PhD students. Our research uses embryonic stem cells (ESC) as a model for embryonic development and T helper cells as a model for adult cell differentiation and is underpinned by our expertise in genomics, biochemical and molecular biology methods.
The post holder will determine the role of G-tract elements embedded in pre-mRNAs in chromatin regulation. They will also establish the contribution of PRC2 RNA binding function to the PRC2 removal from genes activated during cell differentiation and identify other chromatin regulatory elements within pre-mRNAs
The post is funded for 2 years in the first instance but we anticipate funding becoming available to extend this to 3 years.
Key Requirements
The post holder should have a PhD (or be in the process of submitting a PhD) in chromatin regulation, transcriptional control or RNA biology, BSc or equivalent in Molecular Biology, Biochemistry, or a related subject or equivalent experience.
The post holder should have experience of cell culture, quantitative PCR and genomics methodologies or biochemical methods, knowledge of chromatin regulation and/or RNA biology. they should have the ability to organise and prioritise work and to work safely and effectively with a minimum of supervision, skills in cell culture, ideally embryonic stem cell culture and differentiation.
Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.
For enquiries regarding the application process please contact Cancer Institute HR Office [email protected].
Latest time for the submission of applications: 23:59.
UCL Taking Action for Equality
We will consider applications to work on a part-time, flexible and job share basis wherever possible.
Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.