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Higher Scientific Officer – Assay Development and Compound Profiling

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Key Information

Salary: Commencement on the salary range is subject to comparable skills and experience. Future progression is based on annual performance review.

Duration of Contract: Fixed Term for 2 years

Hours per week: 35 hours per week (Full Time)

Closing Date:  Monday 27th November 2023

Job Details

Under the leadership of Dr Rob van Montfort, we are seeking a highly motivated scientist keen to apply small molecule screening science expertise to help progress our cancer drug discovery projects from assay development and hit finding to candidate selection. The successful candidate will develop and run plate-based biochemical and/or cellular screening assays to support the identification and characterisation of small-molecule inhibitors against novel cancer targets using a variety of detection technologies. The successful candidate will be embedded in the Hit Discovery and Structural Design Team but work with multidisciplinary teams.

Key Requirements

The successful candidate must have a significant and broad all-round laboratory experience monitoring small molecule binding and function applied to drug discovery. A good understanding of enzymology would be beneficial, as would prior use of automation equipment for liquid and compound handling used in compound profiling.

Department/Directorate Information

The Centre for Cancer Drug Discovery (CCDD) within the Division of Cancer Therapeutics, is a multidisciplinary ‘bench to bedside’ centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The CCDD’s exciting goal is to discover high quality small molecule drug candidates and to progress these to clinical trial.  Our world-class biologists, chemists and drug metabolism specialists work together focusing on new molecular targets emerging from human genome and ground-breaking cell biology research. This is an exciting and fast-moving area of cancer research and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment. 

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Rob van Montfort via Email on [email protected] 

About The Institute of Cancer Research

Why work for us?

As a member of staff, you’ll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here. 

To apply for this role, please click on the ‘Apply‘ button above.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

Click Here to Apply For The Job



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